Larvae of Andex insignis Sharp (Coleoptera: Adephaga: Dytiscidae) are described. A parsimony analysis of selected taxa of Hydroporinae based on 24 informative larval characters was conducted using the program PAUP*. The 20 most parsimonious trees support a placement of Andex Sharp within the tribe Hyphydrini as part of a clade made up of Desmopachria Babington Hyphydrus Illiger Prismopes Sharp, which is supported by the presence of dorsal metafemoral and mesofemoral setae. Larvae of Andex evolved three unique character states within the Hyphydrini: the presence of several dorsal secondary setae on the prementum, the presence of three frontoclypeal lateral processes in instar III, and the absence of the primary pore TIa.